Figure 1

Kaplan-Meier analysis for RFS by recurrence risks defined by the Cox proportional hazards model. Patients defined as high recurrence risk (dashed line) by the Cox proportional hazards model demonstrated significantly reduced RFS compared to patients defined as low recurrence risk (solid line) in both the (A) discovery (p = 0.0036 by log rank test) and (B) validation (p = 0.009 by log rank test) cohorts