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Table 1 Distribution of claspin positive nuclei/HPF values by histological diagnosis

From: Claspin as a biomarker of human papillomavirus-related high grade lesions of uterine cervix

Histology Claspin-positive nuclei/HPF
Mean (±SD) Median (Min-Max)
WNL (n = 9) 0.4 (±0.8) 0.0 (0.0 -1.8)
CIN1 (n = 19) 7.4 (±13.8) 0.0 (0.0 -51.5)
CIN2 (n = 21) 46.8 (±38.8) 36.5 (1.0-148.6)
CIN3 (n = 16) 72.6 (±46.7) 67.3 (2.0-159.1)
SCC (n = 15) 133.9 (±75.8) 200.0 (11.8-200.0)
  1. p(Kruskall-Wallis) < 0.0001.
  2. HPF, High Power Field; SD, standard deviation; WNL, Within Normal Limit; CIN, Cervical Intraepithelial Neoplasia; SCC, Squamous Cell Carcinoma.