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Table 1 Distribution of claspin positive nuclei/HPF values by histological diagnosis

From: Claspin as a biomarker of human papillomavirus-related high grade lesions of uterine cervix

Histology

Claspin-positive nuclei/HPF

Mean (±SD)

Median (Min-Max)

WNL (n = 9)

0.4 (±0.8)

0.0 (0.0 -1.8)

CIN1 (n = 19)

7.4 (±13.8)

0.0 (0.0 -51.5)

CIN2 (n = 21)

46.8 (±38.8)

36.5 (1.0-148.6)

CIN3 (n = 16)

72.6 (±46.7)

67.3 (2.0-159.1)

SCC (n = 15)

133.9 (±75.8)

200.0 (11.8-200.0)

  1. p(Kruskall-Wallis) < 0.0001.
  2. HPF, High Power Field; SD, standard deviation; WNL, Within Normal Limit; CIN, Cervical Intraepithelial Neoplasia; SCC, Squamous Cell Carcinoma.