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Table 1 Baseline characteristics of severe sepsis patients and control subjects

From: Plasma nuclear and mitochondrial DNA levels as predictors of outcome in severe sepsis patients in the emergency room

  Control n = 33 Study Patients n = 67 p value
Age (y) (mean±SD) 66.3± 8.0 64.8± 13.8 0.57
Male (%) 66.7 65.7 1.00
Underlying diseases    
Diabetes mellitus (%) 54.5 35.8 0.09
Hypertension (%) 60.6 44.8 0.20
Cardiac disease (%) 12.1 11.9 1.00
Systolic blood pressure (mmHg) (mean±SD) 143±15.2 112.2±42.3 <0.001
Diastolic blood pressure (mmHg) (mean±SD) 76.5±10.1 70.5±24.2 0.09
Laboratory data    
Mean (SD) WBC (×10 9 /L) 6.8 (2.5) 15.9 (10.7) <0.001
Mean (SD) Platelet (×10 4 /L) 234.4 (66.4) 158.2 (94.4) <0.001
Mean (SD) Hemoglobin(mg/dL) 13.6 (1.7) 11.9 (2.2) <0.001
Mean (SD) CRP (mg/dL) 1.2 (0.9) 189.6 (124.8) <0.001
Median (IQR) plasma nuclear DNA (ng/mL) 25 (19,41) 436 (216,1140) <0.001
Median(IQR) plasma mitochondrial DNA ( ng/mL) 16 (7,23) 149 (79,304) <0.001
  1. Note: SD, standard deviation; IQR, inter-quartile range; †, laboratory data at presentation in the patients group.