Figure 5
From: Genomic characterization of explant tumorgraft models derived from fresh patient tumor tissue
WNT signalling pathway map enriched with genes up-regulated in tumorgraft-forming tumors. The MetaCore™ pathway analysis suite (GeneGo-Thomson Reuters, St. Joseph, MI) identified a pathway map for WNT signalling. VEGF-A, Frizzled, β-catenin, FAK-1, c-Myc, Laminin 1, XIAP, p21, MELP, and 4E-BP1 present in this pathway were all up-regulated in tumorgraft forming tumors.