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Table 4 Statistically significant by t-test genes down-/up-regulated vs. HuURNA among examined cells. p < 0.01 (≤, ≥), p < 0.05 (<, >)

From: JAK-STAT and AKT pathway-coupled genes in erythroid progenitor cells through ontogeny

Gene Name

Description vs.

F

F

F

C

C

B

C

B

P

B

P

P

ATP6V1B2

ATPase, H + transport, lysosomal 56/58 kDa, V1 sub B2

  

  

>

BRP44

brain protein 44

<

 

 

 

CD24

CD24 molecule

 

>

>

   

CDK2AP2

cyclin-dependent kinase 2 associated prot. 2

>

   

<

<

CLTA

clathrin, light chain (Lca)

  

   

COMT

catechol-O-methyltransferase

 

 

  

CORO1A

coronin, actin binding protein, 1A

  

   

GADD45A

growth arrest and DNA-damage-inducible α

 

<

<

   

ITGB2

integrin, beta 2

     

>

KIFC1

HSET mRNA for kinesin-related protein

   

<

  

LSR

lipolysis stimulated lipoprotein receptor

  

   

PSMB6

proteasome (prosome) subunit, β type, 6

  

<

   

SMAP2

small ArfGAP2

 

<

<

   

SMARCA2

SWI/SNF related, matrix associated, actin depend regul of chromat, subfam a, memb 2

  

>

  

>

STAT6

signal transd & activat of transcr 6, IL-4 ind

 

>

   

THYN1

thymocyte nuclear protein 1

 

<

    

TMX2

thioredoxin-related transmembrane protein 2

 

<

    

TPSB2

tryptase beta 2

 

<

 

<

<

 

VASP

vasodilator-stimulated phosphoprotein

  

   

VIM

vimentin

 

>

>

   

WDR1

WD repeat domain 1

  

 

>

XBP1

X-box binding protein 1

 

>

>

 
  1. nuclear gene encoding mitochondrial protein (ngemp), member (m). Bolded genes – expression >1.5 fold vs. HuURNA. F-fetal liver, C-cord blood, B-bone marrow, P-peripheral blood.