Figure 5From: Suppression of zinc finger protein 467 alleviates osteoporosis through promoting differentiation of adipose derived stem cells to osteoblastsThe expressions of specific osteogenic and adipogenic genes. The expressions of specific osteogenic and adipogenic genes in ADSCs were evaluated by real-time RT-PCR at 0, 3, 7 and 14 days after siRNA-Zfp467 transduction. Specific osteogenic marker Osteocalcin (OCN) (A), Osteopontin (OPN) (B), Collagen I (COL I) (C) and bone sialoprotein (BSP) (D) were up-regulated in si-Zfp467 transduced cells. Specific adipogenic marker lipoprotein lipase (LPL) and peroxisome proliferator-activated receptor gamma (PPARγ) were down-regulated in si-Zfp467 transduced cells (Mean ± SEM, n = 3). * p < 0.05 vs. control group; ** p < 0.01 vs. control group.Back to article page