Table 1 Correlation between AZGP1 expression and clinical and pathological characters in HCC
Variable | AZGP1 protein | ||||
|---|---|---|---|---|---|
|  | All cases | Low expression | High expression |  χ  2 | P valueα |
Age(years) b | Â | Â | Â | 0.134 | 0.714 |
  48 | 119 | 46 (38.7) | 73 (61.3) |  |  |
  ≥ 48 | 127 | 52 (40.9) | 75 (59.1) |  |  |
Mean ± SD(47.9 ± 11.8) |  |  |  |  |  |
Gender | Â | Â | Â | 0.099 | 0.753 |
  Female | 27 | 10 (37.0) | 17(63.0) |  |  |
  Male | 219 | 88(40.2) | 131(59.8) |  |  |
HBsAg | Â | Â | Â | 0.673 | 0.412 |
  Yes | 213 | 87 (40.8) | 126 (59.2) |  |  |
  No | 33 | 11(33.3) | 22 (66.7) |  |  |
AFP (ng/ml) | Â | Â | Â | 6.182 | 0.013 |
  ≤ 20 | 104 | 32 (30.8) | 72 (69.2) |  |  |
  > 20 | 142 | 66 (46.5) | 76 (53.5) |  |  |
Liver cirrhosis | Â | Â | Â | 9.244 | 0.002 |
  Yes | 177 | 81 (45.8) | 96 (54.2) |  |  |
  No | 69 | 17 (24.6) | 52 (75.4) |  |  |
Tumor size (cm) | Â | Â | Â | 0.457 | 0.499 |
  ≤ 5 | 127 | 48 (37.8) | 79 (62.2) |  |  |
  > 5 | 119 | 50 (42.0) | 69 (58.0) |  |  |
Tumor multiplicity | Â | Â | Â | 0.042 | 0.837 |
  Single | 130 | 51 (39.2) | 79 (60.8) |  |  |
  Multiple | 116 | 47 (40.5) | 69 (59.5) |  |  |
Tumor differentiation | Â | Â | Â | 9.347 | 0.025 |
  Well (I) | 33 | 6 (18.2) | 27 (81.8) |  |  |
  Moderate (II) | 125 | 54 (43.2) | 71 (56.8) |  |  |
  Poor (III) | 76 | 35 (46.1) | 41 (53.9) |  |  |
Undifferentiation (IV) | 12 | 3 (25) | 9 (75) | Â | Â |
Clinical Stage | Â | Â | Â | 2.154 | 0.541 |
  I | 16 | 5 (31.3) | 11 (68.7) |  |  |
  II | 93 | 33 (35.5) | 60 (61.5) |  |  |
  III | 106 | 46 (43.4) | 60 (56.6) |  |  |
  IV | 31 | 14 (45.2) | 17 (54.8) |  |  |
Vascular invasion | Â | Â | Â | 1.966 | 0.161 |
  Yes | 73 | 34 (46.6) | 39 (53.4) |  |  |
  No | 173 | 64 (37.0) | 109 (63.0) |  |  |