Fig. 8

Comparison of AUC between different random forest models. A Model B + vs. Model A +. B Model C + vs. Model A +. Model A +: baseline predictive model for total group (N = 346). Model B +: combined model of high cumulative MMI dosage group (≥ 1730 mg, average ≥ 20 mg/day, N = 114) at 3 months of therapy. Model C +: combined model of medium–low cumulative MMI dosage group (< 1730 mg, average < 20 mg/day, N = 232) at 3 months of therapy