Table 1 Characteristics of patients with colorectal carcinoma in situ and neoplastic polyps
Noncarcinoma in situ (n = 2239) | Carcinoma in situ (n = 90) | P | Nonneoplastic polyps (n = 536) | Neoplastic polyps(n = 1793) | P | |
|---|---|---|---|---|---|---|
Sex (male/female) | 1446/793 | 66/24 | 0.088 | 331/205 | 1181/612 | 0.080 |
Age, M(IQR) | 63.00(17.00) | 66.00(11.00) | 0.004 | 59.00(21.00) | 64.00(16.00) | < 0.0001 |
Diameter of polyps | 0.80(0.60) | 1.50(1.50) | < 0.0001 | 0.60(0.30) | 0.80(0.90) | < 0.0001 |
< 1.0 cm, n (%) | 1370(61.19) | 14(15.56) | 422(78.73) | 962(53.65) | ||
≥ 1.0 cm, n (%) | 869(38.81) | 76(84.44) | 114(21.27) | 831(46.35) | ||
Solitary polyp, n (%) | 1164(52.0) | 32(35.6) | 0.002 | 314(58.6) | 882(49.2) | <0.0001 |
Multiple polyps | 1075(48.0) | 58(64.4) | 222(41.42) | 911(50.81) | ||
Number of colorectal polyps | < 0.0001 | 0.002 | ||||
< 3, n (%) | 1641(73.29) | 47(52.22) | 416(77.6) | 1272(70.9) | ||
≥ 3, n (%) | 598(26.7) | 43(47.8) | 120(22.4) | 521(29.1) | ||
Schistosome eggs | 38/2201 | 6/84 | 0.006 | 8/528 | 36/1757 | 0.442 |
Hp infection | 158(7.1) | 5(5.6) | 0.584 | 41(7.6) | 122(6.8) | 0.501 |
Hypertension (Yes/No) | 603/1636 | 25/65 | 0.859 | 128/408 | 500/1293 | 0.067 |
Diabetes (Yes/No) | 82/2157 | 5/85 | 0.385 | 23/513 | 64(1729) | 0.440 |
CHD (Yes/No) | 13/2226 | 0/90 | 1.000 | 3/533 | 10/1783 | 1.000 |
MAFLD (Yes/No) | 318/1921 | 8/82 | 0.154 | 81/455 | 245/1548 | 0.397 |
WBC*10^9/L | 6.05(2.09) | 6.24(2.38) | 0.181 | 6.07(2.07) | 6.04(2.11) | 0.845 |
RBC*10^12/L | 4.54(0.65) | 4.50(0.65) | 0.267 | 4.54(0.66) | 4.54(0.64) | 0.208 |
Hemoglobin, g/L | 138.91(20.00) | 138.91(24.00) | 0.617 | 139.00(21.00) | 138.91(20.00) | 0.406 |
PLT*10^9/L | 213.00(68.00) | 210.50(67.00) | 0.631 | 213.50(67.00) | 213.00(69.00) | 0.902 |
Albumin, g/L | 43.65(4.00) | 43.65(2.70) | 0.005 | 43.65(4.00) | 43.65(5.00) | 0.070 |
Total bilirubin, umol/L | 11.90(5.50) | 12.11(3.18) | 0.678 | 11.65(5.70) | 12.10(5.20) | 0.522 |
ALT, U/L | 19.00(14.00) | 23.84(11.00) | 0.412 | 20.00(15.00) | 19.00(13.00) | 0.412 |
AST, U/L | 20.00(8.00) | 21.50(5.00) | 0.302 | 19.00(8.00) | 20.00(7.00) | 0.302 |
γ-GT, U/L | 25.00(18.10) | 34.09(17.10) | 0.258 | 24.00(19.10) | 26.00(18.10) | 0.070 |
ALP, U/L | 73.00(20.00) | 73.05(11.00) | 0.051 | 73.00(22.00) | 73.05(20.00) | 0.843 |
LDH, U/L | 160.08(32.00) | 160.08(13.60) | 0.866 | 160.08(33.80) | 160.08(31.00) | 0.808 |
Creatinine, umol/L | 74.60(20.00) | 74.60(13.00) | 0.345 | 74.00(21.00) | 74.60(19.00) | 0.494 |
Uric acid, umol/L | 330.48(98.00) | 330.48(48.50) | 0.221 | 330.48(110.00) | 330.48(89.00) | 0.512 |
TC, mmol/L | 4.51(0.97) | 4.51(0.51) | 0.103 | 4.51(0.92) | 4.51(0.96) | 0.488 |
TG, mmol/L | 1.60(0.72) | 1.68(0.48) | 0.157 | 1.58(0.75) | 1.62(0.71) | 0.844 |
AFP, ng/mL | 3.01(1.26) | 3.01(1.12) | 0.288 | 2.88(1.42) | 3.01(1.21) | 0.315 |
CEA, ng/mL | 2.48(1.28) | 2.57(0.53) | 0.450 | 2.34(1.30) | 2.56(1.26) | 0.146 |
CA125, U/mL | 10.17(3.77) | 10.52(2.36) | 0.240 | 9.75(4.28) | 10.34(3.60) | 0.184 |
CA199, U/mL | 10.44(6.01) | 11.25(3.42) | 0.055 | 9.60(6.09) | 10.97(5.88) | 0.023 |
CA724, U/mL | 2.12(3.18) | 4.29(2.77) | 0.002 | 2.05(3.22) | 2.20(3.16) | 0.457 |
CA211, ng/mL | 2.61(1.05) | 2.61(0.79) | < 0.0001 | 2.56(1.11) | 2.61(1.05) | 0.287 |