Fig. 4
Analysis of DMRs in different tissues of human NTDs methylome. A, D PCA plots illustrating spinal cord and brain tissue samples involved in DMRs analysis, respectively. B, E Heatmaps displaying the DMRs in the spinal cord and brain of NTDs methylome, respectively, with the top DMRs being shown. C, F Volcano plots visualizing DMRs in the spinal cord and brain, respectively, with the top DMRs being shown. G, I GSEA GO analysis of genes corresponding to DMRs in the spinal cord and brain of NTDs methylome, respectively. H, J GSEA KEGG analysis of genes corresponding to DMRs in the spinal cord and brain of NTDs methylome, respectively