Table 1 General Characteristics of female non-diabetic participants and type 2 diabetic patients
From: ANGPTL3 is a novel HDL component that regulates HDL function
Non-diabetic | Type 2 diabetic | P value | |
|---|---|---|---|
n | 37 | 35 | |
Hypertension (%) | 12 (32.43) | 12 (34.29) | 0.8676 |
Coronary heart disease (%) | 2(5.41) | – | 0.1630 |
Medications (%) | |||
Lipid-lowering drugs (0,1) | 1 (2.70) | – | 0.3274 |
Anti-hypertensive (0,1) | 5 (13.51) | 3 (8.57) | 0.5048 |
Insulin (0,1) | – | 3 (8.57) | 0.0689 |
Metformin (0,1) | – | 12 (34.29) | < 0.0001 |
Mean of characteristics | |||
Age(year) | 53.92 (5.87) | 56.60 (5.64) | 0.052 |
Body mass index (kg/m2) | 27.00 (4.42) | 26.64 (4.33) | 0.727 |
Systolic blood pressure (mm Hg) | 129.64 (19.18) | 129.78 (17.26) | 0.974 |
Diastolic blood pressure (mm Hg) | 76.38 (12.00) | 73.70 (11.04) | 0.328 |
Fasting blood glucose (mg/dL) | 5.04 (0.42) | 9.51 (2.78) | < 0.001 |
Insulin (pmol/L) | 58.04 (24.77) | 71.41 (42.59) | 0.112 |
Homa-B,% | 98.51 (24.85) | 38.7 (22.1) | < 0.001 |
Homa-IR,% | 1.10 (0.37) | 1.5 (1.0) | 0.048 |
UA (μmol/L) | 242.86 (51.56) | 241.71 (64.61) | 0.381 |
Total cholesterol (mmol/L) | 200.03 (33.86) | 204.56 (29.31) | 0.546 |
Triglyceride (mg/dL) | 145.61 (78.34) | 127.13 (56.25) | 0.253 |
LDL-c (mmol/L) | 121.12 (30.76) | 127.17 (26.99) | 0.379 |
HDL-c (mmol/L) | 55.39 (13.36) | 53.43 (10.60) | 0.494 |
HDL components | |||
Apolipoprotein A‐I (μg/mL) | 11.28 (3.61) | 9.88 (1.99) | 0.045 |
Serum amyloid A (μg/L) | 795.09 (148.91) | 1115.40 (285.66) | < 0.001 |
Phospholipid (mg/dL) | 798.07 (310.82) | 1001.66 (353.09) | 0.011 |
Sphingosine-1-phosphate (ng/L) | 1318.21 (404.95) | 2035.57 (864.13) | < 0.001 |
Triglyceride (mg/dL) | 408.13 (67.10) | 1054.27 (178.20) | < 0.001 |