Fig. 5
From: ANGPTL3 is a novel HDL component that regulates HDL function
HDL function was decreased in ANGPTL3−/− mice. A Phenotype determination of ANGPTL3 knock out mice (ANGPTL3−/−) and wild type mice (WT) in the same nest by RT-PCR. B The ANGPTL3 mRNA levels in liver tissues of WT and ANGPTL3−/− mice by RT-qPCR. C Plasma ANGPTL3 levels in WT and ANGPTL3−/− mice. The ANGPTL3 expression in plasma of WT and ANGPTL3−/− mice were analyzed by ELISA. D. Total cholesterol levels in plasma of WT and ANGPTL3−/− mice. E Total triglyceride levels in plasma of WT and ANGPTL3−/− mice. F LDL-c levels in plasma of WT and ANGPTL3−/− mice. G HDL-c levels in plasma of WT and ANGPTL3−/− mice. H HDL-apoA-I in plasma of WT and ANGPTL3−/− mice. I HDL-SAA levels in plasma of WT and ANGPTL3−/− mice. J HDL-PL levels in plasma of WT and ANGPTL3−/− mice. K HDL-S1P levels in plasma of WT and ANGPTL3−/− mice. L The percentage of cholesterol efflux to HDL isolated from plasma in WT and ANGPTL3−/− mice