Table 1 Demographic and clinical characteristics of the patients with psoriasis
Patient numbers | 3 | 5 | p-value | 14 | 14 | 14 | p-value | 10 | 10 | p-value |
|---|---|---|---|---|---|---|---|---|---|---|
Characteristics | Screening | Validation | Treatment response | |||||||
PASI < 5 | 10 ≥ PASI | 0 < PASI < 5 | 5 \(\le\) PASI < 10 | 10 ≥ PASI | Poor responders* | Good responders* | ||||
Age (mean ± SD, yr) | 36.3 ± 5.6 | 52.6 ± 15.4 | 0.1124 | 36.3 ± 9.3 | 40.1 ± 13.4 | 37.1 ± 11.6 | 0.6837 | 39.8 ± 15.8 | 41.7 ± 15.5 | 0.7890 |
Sex (M:F) | 2:1 | 4:1 | Â | 7:7 | 10:4 | 8:6 | Â | 7:3 | 7:3 | Â |
BMI (mean ± SD, kg/m2 or lb/ inches \(\times\) 703) | 24.2 ± 1.1 | 25.5 ± 1.0 | 0.2032 | 25.5 ± 4.2 | 24.1 ± 3.3 | 26.4 ± 5.1 | 0.3755 | 26.5 ± 3.2 | 25.4 ± 2.4 | 0.3888 |
Initial PASI (mean ± SD) | 3.9 ± 0.5 | 13.6 ± 1.9 | 0.0002 | 3.5 ± 1.0 | 6.5 ± 1.0 | 18.9 ± 6.0 |  < 0.0001 | 10.8 ± 5.1 | 13.1 ± 5.7 | 0.3251 |
Initial BSA (mean ± SD, %) | 4.7 ± 2.1 | 23.4 ± 4.0 | 0.0003 | 6.1 ± 4.2 | 9.4 ± 5.3 | 31.9 ± 12.3 |  < 0.0001 | 15.7 ± 16.1 | 20.6 ± 11.5 | 0.4457 |
Disease duration (yr) | 6.3 ± 3.3 | 12.8 ± 8.9 | 0.2486 | 10.5 ± 8.8 | 10.0 ± 8.3 | 12.5 ± 9.8 | 0.7575 | 10.8 ± 5.9 | 13.8 ± 5.2 | 0.2430 |
Psoriasis onset age(mean ± SD, yr) | 30.0 ± 2.4 | 39.8 ± 11.8 | 0.1749 | 25.8 ± 7.3 | 30.1 ± 11.8 | 24.7 ± 13.8 | 0.4484 | 29.0 ± 16.3 | 27.9 ± 16.3 | 0.8816 |
Joint involvement (%) | 0 | 0 |  > 0.9999 | 0 | 0 | 14.2 | 0.1225 | 0 | 0 |  > 0.9999 |
Nail involvement (%) | 66.7 | 80 |  > 0.9999 | 21.4 | 14.2 | 42.9 | 0.2017 | 50 | 40 |  > 0.9999 |