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Table 4 Factors of poor prognosis subgroups by using Cox regression and Bonferroni correction for multiple comparisons

From: Increased risk of psychiatric disorder in patients with hearing loss: a nationwide population-based cohort study

Sensitivity test

Hearing loss

With

Without (Reference)

With vs. without (Reference)

Poor prognosis subgroups

Events

PYs

Rate (per 105 PYs)

Events

PYs

Rate (per 105 PYs)

Adjusted HR

Lower 95% CI

Upper 95% CI

P

Overall

Overall

13,341

828,013.26

1611.21

31,250

3,377,815.10

925.15

2.587

1.723

3.346

< 0.001

Mental disoredes

11,084

828,013.26

1338.63

24,874

3,377,815.10

736.39

2.701

1.796

3.495

 < 0.001

Anxiety

2677

828,013.26

323.30

5211

3,377,815.10

154.27

3.114

2.076

4.025

< 0.001

Depression

3167

828,013.26

382.48

5955

3,377,815.10

176.30

3.225

2.146

4.168

< 0.001

Bipolar

1523

828,013.26

183.93

4112

3,377,815.10

121.74

2.245

1.496

2.904

< 0.001

Sleep disorders

1912

828,013.26

230.91

4512

3,377,815.10

133.58

2.568

1.710

3.323

< 0.001

PTSD/ASD

230

828,013.26

27.78

413

3,377,815.10

12.23

3.371

2.248

4.356

< 0.001

Dementia

188

828,013.26

22.70

522

3,377,815.10

15.45

2.182

1.457

2.833

< 0.001

Eating disorders

311

828,013.26

37.56

811

3,377,815.10

24.01

2.234

1.549

3.007

< 0.001

SRD

296

828,013.26

35.75

823

3,377,815.10

24.36

2.179

1.452

2.820

< 0.001

Psychotic disorders

270

828,013.26

32.61

772

3,377,815.10

22.86

2.118

1.412

2.740

< 0.001

Autism

58

828,013.26

7.00

201

3,377,815.10

5.95

1.749

1.167

2.263

< 0.001

Other mental disorders

452

828,013.26

54.59

1542

3,377,815.10

45.65

1.775

1.183

2.297

< 0.001

Suicide

156

828,013.26

18.84

597

3,377,815.10

17.67

1.583

1.048

2.049

0.002

All-caused mortality

2101

828,013.26

253.74

5779

3,377,815.10

171.09

2.204

1.467

2.879

< 0.001

In the first year excluded

Overall

12,007

776,918.33

1545.46

28,108

3,166,702.49

887.61

2.586

1.723

3.345

< 0.001

Mental disoredes

9977

776,918.33

1284.18

22,388

3,166,702.49

706.98

2.698

1.797

3.490

< 0.001

Anxiety

2408

776,918.33

309.94

4688

3,166,702.49

148.04

3.110

2.071

4.022

< 0.001

Depression

2851

776,918.33

366.96

5354

3,166,702.49

169.07

3.224

2.147

4.170

< 0.001

Bipolar

1371

776,918.33

176.47

3697

3,166,702.49

116.75

2.245

1.495

2.904

< 0.001

Sleep disorders

1724

776,918.33

221.90

4058

3,166,702.49

128.15

2.572

1.713

3.327

< 0.001

PTSD/ASD

209

776,918.33

26.90

389

3,166,702.49

12.28

3.253

2.167

4.207

< 0.001

Dementia

169

776,918.33

21.75

470

3,166,702.49

14.84

2.177

1.450

2.816

< 0.001

Eating disorders

280

776,918.33

36.04

729

3,166,702.49

23.02

2.326

1.549

3.008

< 0.001

SRD

266

776,918.33

34.24

744

3,166,702.49

23.49

2.165

1.442

2.800

< 0.001

Psychotic disorders

243

776,918.33

31.28

691

3,166,702.49

21.82

2.129

1.418

2.754

< 0.001

Autism

52

776,918.33

6.69

183

3,166,702.49

5.78

1.720

1.146

2.225

< 0.001

Other mental disorders

404

776,918.33

52.00

1385

3,166,702.49

43.74

1.766

1.176

2.284

< 0.001

Suicide

131

776,918.33

16.86

519

3,166,702.49

16.39

1.528

1.018

1.977

0.033

All-caused mortality

1899

776,918.33

244.43

5201

3,166,702.49

164.24

2.211

1.472

2.859

< 0.001

In the first 5 years excluded

Overall

6657

568,149.17

1171.70

17,675

2,322,248.05

761.12

2.287

1.523

2.958

< 0.001

Mental disoredes

5529

568,149.17

973.16

14,068

2,322,248.05

605.79

2.386

1.589

3.086

< 0.001

Anxiety

1366

568,149.17

240.43

2947

2,322,248.05

126.90

2.814

1.874

3.640

< 0.001

Depression

1611

568,149.17

283.55

3369

2,322,248.05

145.07

2.903

1.934

3.755

< 0.001

Bipolar

760

568,149.17

133.77

2326

2,322,248.05

100.16

1.984

1.321

2.566

< 0.001

Sleep disorders

954

568,149.17

167.91

2551

2,322,248.05

109.85

2.271

1.512

2.937

< 0.001

PTSD / ASD

55

568,149.17

9.68

245

2,322,248.05

10.55

1.363

0.908

1.763

0.101

Dementia

74

568,149.17

13.02

303

2,322,248.05

13.05

1.483

0.988

1.918

0.072

Eating disorders

155

568,149.17

27.28

459

2,322,248.05

19.77

2.050

1.366

2.652

< 0.001

SRD

158

568,149.17

27.81

461

2,322,248.05

19.85

2.081

1.386

2.691

< 0.001

Psychotic disorders

135

568,149.17

23.76

432

2,322,248.05

18.60

1.897

1.264

2.454

< 0.001

Autism

35

568,149.17

6.16

111

2,322,248.05

4.78

1.914

1.275

2.476

< 0.001

Other mental disorders

226

568,149.17

39.78

864

2,322,248.05

37.21

1.588

1.058

2.054

< 0.001

Suicide

80

568,149.17

14.01

330

2,322,248.05

14.21

1.465

0.976

1.895

0.089

All-caused mortality

1048

568,149.17

184.52

3277

2,322,248.05

141.11

1.942

1.294

2.512

< 0.001

  1. PYs Person-years; Adjusted HR Adjusted Hazard ratio: Adjusted for the variables listed in Table 3; CI confidence interval
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Journal of Translational Medicine

ISSN: 1479-5876

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