Fig. 5From: CRISPR/Cas9-edited ROS1 + non-small cell lung cancer cell lines highlight differential drug sensitivity in 2D vs 3D cultures while reflecting established resistance profilesMultiplex TKI screening in spheroids. 120 h post-TKI treatment 17 nM of ROS1 wild type and mutant HCC78 spheroids. Magenta: Orbits® label-free organoid segmentation defining the total spheroid area. Green: fluorescence cytotox green signal staining dead cellsBack to article page