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Table 1 TINAGL1 and COL1A1 expression is associated with overall survival of DGC patients in the GSE15459 dataset

From: Tubulointerstitial nephritis antigen-like 1 from cancer-associated fibroblasts contribute to the progression of diffuse-type gastric cancers through the interaction with integrin β1

Variable

n (%)

Univariate

Multivariate

HR (95% CI)

P-value

HR (95% CI)

P-value

TINAGL1/COL1A1

 Others

64 (85.3)

 

 

 TINAGL1 + /COL1A1 + 

11 (14.7)

2.41 (1.09–5.28)

0.029

3.78 (1.37–10.41)

0.010

Age

 > 65

31 (41.3)

 

 

 65 ≥

44 (58.7)

0.80 (0.43–1.51)

0.498

0.77 (0.36–1.68)

0.516

Gender

 Female

39 (52.0)

 

 

 Male

36 (48.0)

1.55 (0.83–2.90)

0.170

0.93 (0.45–1.94)

0.845

Stage

 I

9 (12.0)

 

 

 II

12 (16.0)

7.98 (0.98–65.10)

0.052

10.87 (1.24–95.02)

0.031

 III

31 (41.3)

9.49 (1.25–72.24)

0.030

12.82 (1.57–104.51)

0.017

 IV

23 (30.7)

33.96 (4.36–264.71)

0.001

57.30 (6.64–494.59)

< 0.001

Subtype

 Metabolic

16 (26.2)

 

 

 Proliferative

12 (19.7)

1.51 (0.54–4.20)

0.427

0.72 (0.25–2.08)

0.541

 Mesenchymal

33 (54.1)

1.60 (0.71–3.63)

0.256

0.98 (0.40–2.41)

0.968

  1. Cox regression model
  2. HR hazard ratio, CI confidence interval