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Table 7 Association of level of MSI with dMMR status in the cancer cohort

From: Comparison of standard mismatch repair deficiency and microsatellite instability tests in a large cancer series

 

MSI-H

MSI-H

MSI-H

MSI-H

MSI-L

Altered markers

5

4

3

2

1

All cancers

 MSI (147)

56 (38.1%)

21 (14.3%)

5 (3.4%)

9 (6.1%)

56(38.1%)

 dMMR (100)

53 (53.0%)

19 (19.0%)

4 (4.0%)

6 (6.0%)

18 (18.0%)

Colorectal

 MSI (114)

46 (40.4%)

18 (15.8%)

3 (2.6%)

4 (3.5%)

43 (37.7%)

 dMMR (67)

44 (56.4%)

16 (20.5%)

3 (3.8%)

2 (2.6%)

13 (16.7%)

Non-colorectal

 MSI (33)

10 (30.3%)

3 (9.1%)

2 (6.1%)

5 (15.2%)

13 (39.4%)

 dMMR (22)

9 (40.9%)

3 (13.6%)

1 (4.5%)

4 (18.2%)

5 (22.7%)

  1. dMMR mismatch repair deficiency, MSI-H microsatellite instability-high, MSI-L microsatellite instability-low