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Table 4 Predictive power of MSI PCR for MMR IHC status

From: Comparison of standard mismatch repair deficiency and microsatellite instability tests in a large cancer series

Cancer type

Sensitivity (%)

Specificity (%)

PPV (%)

NPV (%)

% Agreement

Kappa value

Colorectal

41.4

98.5

91.6

80.5

81.9

0.476

Non-colorectal

32.0

96.4

80.0

75.1

76.3

0.339

  1. kappa Cohen’s kappa (95% CI), NPV negative predictive power, PPV positive predictive power
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Journal of Translational Medicine

ISSN: 1479-5876

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