Table 3 Comparison of MMR immunohistochemistry and MSI PCR results in our cancer cohort
n | MSS n(%) | MSI-L n(%) | MSS/MSI-L n(%) | MSI-H n(%) | discrepancy n(%) | |
|---|---|---|---|---|---|---|
All cancers | 703 | 136 (19.3) | ||||
pMMR | 496 | 448 (90.3) | 38 (7.7) | 486 (98.0) | 10 (2.0) | 10 (2.0) |
dMMR | 207 | 108 (52.2) | 18 (8.7) | 126 (60.9) | 81 (39.1) | 126 (60.9) |
Colorectal | 543 | 98 (18.0) | ||||
pMMR | 386 | 350 (90.7) | 30 (7.8) | 380 (98.4) | 6 (1.7) | 6 (1.6) |
dMMR | 157 | 79 (50.3) | 13 (8.3) | 92 (58.6) | 65 (41.4) | 92 (58.6) |
Non-colorectal | 160 | 38 (23.8) | ||||
pMMR | 110 | 98 (89.1) | 8 (7.3) | 106 (96.4) | 4 (3.6) | 4 (3.6) |
dMMR | 50 | 29 (58.0) | 5 (10.0) | 34 (68.0) | 16 (32.0) | 34 (68.0) |