Fig. 1

HFHS diet induces obesity and lipid metabolic disturbances in female mice. A Body weights of control and HFHS mice (control, n = 8; HFHS, n = 7). B Levels of fat mass and lean mass from control and HFHS mice detected by dual-energy X-ray absorptiometry (control, n = 8; HFHS, n = 5). C Serum levels of total cholesterol (TC) (control, n = 9; HFHS, n = 7). D Serum levels of low-density lipoprotein (LDL) (control, n = 8; HFHS, n = 7). E Serum levels of high-density lipoprotein (HDL) (control, n = 9; HFHS, n = 7). F Serum levels of triglyceride (TG) (control, n = 7; HFHS, n = 8). G Representative H&E staining images of SAT and VAT in control and HFHS mice. H Representative H&E and Oil Red O staining images of livers in control and HFHS mice. Data are presented as mean ± SEM, **P < 0.01, ***P < 0.001