Fig. 1
From: Recent advances of m6A methylation in skeletal system disease
Structural schematic diagram of reversible and dynamic posttranscriptional m6A modification of RNA. a. In the nucleus, methyltransferases and demethylases regulated the m6A modifications of target mRNAs. b. In the nucleus, m6A readers such as hnRNPA2B1 regulated the splicing process of target mRNAs. c. In the cytoplasm, m6A readers such as YTHDF1 regulated the translation process of target mRNAs. d. In the cytoplasm, m6A readers such as IGF2BP1 regulated the stability of target mRNAs. e. In the cytoplasm, m6A readers such as YTHDF3 mediated the degradation of target mRNAs