Fig. 5

Pyroptotic cell death induced by ZIKV-LAV infection in human GBM cells. A Western blot detection of gasdermin D (GSDMD) cleavage in infected DBTRG and T98G cell lysates at day 5 post-infection. B–C Quantification of GSDMD cleavage from western blot data normalized to β-actin expression. Data are shown as fold-change in percentage of (%) GSDMD cleavage relative to mock-infected cells. D–E Luminescence-based detection of IL-1β secreted by infected cells. Data are shown as mean ± SD. Means were compared by Kruskal–Wallis test with Dun’s post-hoc correction. *p < 0.05; **p < 0.005; ***p < 0.001