Table 1 Characteristics of patients in the training and validation cohorts
Characteristic | Training cohort (n = 159) | Validation cohort (n = 105) |
|---|---|---|
Sex | ||
 Female | 69 (43.39%) | 49 (46.67%) |
 Male | 64 (40.25%) | 43 (40.95%) |
 NA | 26 (16.36%) | 13 (12.38%) |
Age (years) | ||
 ≤ 60 | 33 (20.75%) | 21 (20.00%) |
 > 60 | 100 (62.89%) | 71 (67.62%) |
 NA | 26 (16.36%) | 13 (12.38%) |
Smoking status | ||
 Smoker | 111 (69.81%) | 81 (77.14%) |
 Non-smoker | 22 (13.83%) | 11 (10.48%) |
 NA | 26 (16.36%) | 13 (12.38%) |
TMB | ||
 High | 47 (29.56%) | 27 (25.71%) |
 Low | 61 (38.36%) | 47 (44.76%) |
 NA | 51 (32.08%) | 31 (29.53%) |
PD-L1 expression | ||
 High | 15 (9.44%) | 10 (9.53%) |
 Low | 94 (59.11%) | 63 (60.00%) |
 NA | 50 (31.45%) | 32 (30.47%) |
Response status | ||
 Response | 38 (23.90%) | 23 (21.91%) |
 Non-response | 121 (76.10%) | 82 (78.09%) |