Fig. 3

Predictive accuracy of the developed models, and subgroup analysis of SE-derived signatures. Time-dependent ROC curves of developed models for overall survival (A) and lung metastasis-free survival (B) at 3-, 5-, 10-year in the training and validation sets respectively. Kaplan-Meier analysis of overall survival (C) and lung metastasis-free survival (D) for all 212 patients according to the SE-derived signatures stratified by clinicopathological risk factors.