Fig. 3

Relationship of cardiac FAP with members of the TGF-β signaling pathway. A Relative mRNA expression levels of TGFB2 and TGFB3 in control subjects (n = 10) and patients with heart failure (n = 26). B Correlation of FAP mRNA levels with TGFB2 mRNA levels. Bars represent mean ± SEM values. Figures reflect the relative expression (in arbitrary units) extracted from the mRNA-seq analysis for both patients and controls to provide an idea of the average expression of each of the molecules A.u., arbitrary units. Correlation was determined using Spearman’s correlation coefficient. Control subjects (gray), heart failure patients (light blue). *p < 0.05. TGFB transforming growth factor beta