Fig. 2

Expression of UBXDF in cancers. A The boxplot shows the mRNA expression levels of UBXDF based on the TCGA dataset. B Heatmap shows differential UBXDF expression (normal vs. tumour) in TCGA. C Co-expression network among UBXDF and VCP (p97). D Survival contribution of UBXDF genes in 33 cancer types. The coloured border represents a significance level of less than 0.05. E Trend plot presents the trend of gene expression from stage I to stage IV. F, G Correlations between UBXDF expression and DNAss or RNAss. H Representative images of UBXDF (except UBXN8) protein in the U-2-OS cell line. I, J Correlations between UBXDF and drug sensitivity data from the GDSC or CTRP.