Fig. 6
CD33 CARKR T cells are effective in vitro A, the CAR expression before and after cell sorting. B, cytotoxicity of CD33 CAR T cells, CD33KR CAR T cells, and PCDH CAR T cells that co-cultured with U937CD33 cells at different effector: target (E:T) ratios. C, CAR T cell number, the CAR expression, and CD69 positivity expression in CD33 CAR T cells and CD33KR CAR T cells. A–C, were representative data from at least three independent experiments. Assays were performed on day 10 after the initial T-cell culture. Unless otherwise noted, P values are determined by unpaired t-tests. The numbers on the graphs are P values