Fig. 4

Galectins are highly expressed in myeloid leukemia cells A, Heat maps showing suppressive genes differentially expressed between myeloid and lymphoid leukemia cell lines and between primary AML and ALL samples. Genes are those that are up or down-regulated more than two-fold, except galectin-9 in primary AML and ALL samples. AML and ALL primary samples had two biological replicates, respectively. B–E, Histograms showing the expression of galectin-1, galectin-3, galectin-12, and galectin-9 in AML and ALL cell lines; Histograms and the MFI of galectin-1, galectin-3,and galectin-12 in primary AML and ALL samples. Data shown are mean ± SEM of three experimental replicates