Fig. 3
LIPCAR is transported by cardiac EVs, predominantly by lEVs, in non-failing and failing heart patients. A Non-failing (NF) and heart failing (HF) patients were age-matched. B Isolation procedure of EVs from cardiac tissue. lEVs: large EVs, sEVs: small EVs. C, D Comparison of LIPCAR expression in lEVs and sEVs isolated from heart of NF (C) and HF (D) patients using the 2 pairs of primers (n = 9/group). β-actin was used for normalization. Statistical significance was determined by Wilcoxon-Mann Whitney test and significant P values are indicated