Fig. 3

PLOD3 promotes CRC cell migration and invasion. A–C Transwell filter migration and invasion assays to determine the PLOD3 knockdown or overexpression on the migration ability of CRC cells; D Western blotting to measure the expression of VIM and CDH1 after PLOD1 knockdown. E The quantification and statistical analysis on the expression levels of CDH1 and VIM and displayed them in the form of histograms. Data are shown as the mean ± SEM (three independent experiments). *P < 0.05; **P < 0.01; ***P < 0.001)