Fig. 2From: PLOD3 facilitated T cell activation in the colorectal tumor microenvironment and liver metastasis by the TNF-α/ NF-κB pathwayPLOD3 strengthens the CRC cell proliferation in vitro. A, B, C qRT-PCR analysis of PLOD3 mRNA levels normalized to GAPDH in the CRC cell lines stably transduced with PLOD3-targeting shRNA or control shRNA; D mRNA levels of PLOD3 upon PLOD3 overexpression by lentivirus‐PLOD3; E, F, G, H CCK-8 assays to determine the proliferation of PLOD3 knockdown or over-expression in the CRC cells; I–K Colony-forming assays to determine the effects of PLOD3 overexpression or knockdown on the growth of CRC cells. Data are shown as the mean ± SEM (three independent experiments). *P < 0.05; **P < 0.01; ***P < 0.001)Back to article page