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Fig. 4 | Journal of Translational Medicine

Fig. 4

From: Integrating single-cell and bulk RNA sequencing data unveils antigen presentation and process-related CAFS and establishes a predictive signature in prostate cancer

Fig. 4

Identification of antigen processing and presentation-related subtypes in CAFs. A UMAP visualization of NMF clustering subtypes based on APP-related genes in CAFs. B Pseudotime trajectory analysis of NMF clusters. C Definition of APP-related subtypes in CAFs. Cell‒cell communication from APP-related CAFs to epithelial cells (D) and T cells (E). F Associations between APP-related CAF subtypes and previous signatures. G Heatmap demonstrating differential average expression levels of common signaling pathway genes between the two APP-related subtypes

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Journal of Translational Medicine

ISSN: 1479-5876

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