Fig. 3
From: RUNX1 knockdown induced apoptosis and impaired EMT in high-grade serous ovarian cancer cells
Functional and pathway enrichment analysis of the RUNX1 knockdown expression profiling in ovarian cancer cells. Heat map demonstrated the significantly changed genes hierarchical cluster analysis of RUNX1 knockdown transcription profiles in SKOV3 ovarian cancer cells. The significantly changed genes of RUNX1 vs control were screened and identified (A). Representative Molecular Complex Detection (MCODE) network node demonstrated the connection of significantly changed genes regulated by RUNX1 knockdown (B). Representative Molecular clusters were enriched. Left panel, heatmap of the top 20 enriched terms (C). Metascape analysis revealed a Network of enriched sets colored by ID. Threshold value: 0.3 kappa score; similarity score > 0.3. b Heatmap colored arranged by p -values