Skip to main content
Fig. 5 | Journal of Translational Medicine

Fig. 5

From: Altered splicing machinery in lung carcinoids unveils NOVA1, PRPF8 and SRSF10 as novel candidates to understand tumor biology and expand biomarker discovery

Fig. 5

Effect of NOVA1, PRPF8 and SRSF10 modulation on lung carcinoid cell lines. A. NOVA1, PRPF8 and SRSF10 basal expression levels in UMC-11 and NCI-H727 cell lines adjusted by ACTB expression levels. B. Validation of NOVA1, PRPF8 and SRSF10 silencing in lung carcinoid cell lines by qPCR. Data are expressed as a mean ± SEM as percentage of control (scramble; set at 100%) (n = 3). C. Proliferation rate of NOVA1, PRPF8 and SRSF10-silenced cells compared to control scramble-transfected lung carcinoid cells (n = 3). D. Colony formation capacity of NOVA1, PRPF8 and SRSF10-silenced cells compared to control scramble-transfected lung carcinoid cells (scramble; set as 100%). Representative images of colony formation (n = 3)

Back to article page

Journal of Translational Medicine

ISSN: 1479-5876

Contact us