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Fig. 3 | Journal of Translational Medicine

Fig. 3

From: Crosstalk and plasticity driving between cancer-associated fibroblasts and tumor microenvironment: significance of breast cancer metastasis

Fig. 3

Communication between breast CAFs and tumor. CAFs regulates the growth and invasion of cancer cells by secreting cytokines, exosomes, ECM and stromal cells. A The mode of action of cytokines (growth factors, chemokines, interleukins) B CAFs cut off the transfer pathway by targeting exosomes C Remodeling of the extracellular matrix D Relationship between CAFs and stromal cells (mainly macrophages)

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Journal of Translational Medicine

ISSN: 1479-5876

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