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Table 6 Risk of individual outcome according to treatment with statin in the nested case–control study

From: Impact of statin treatment on cardiovascular risk in patients with type 1 diabetes: a population-based cohort study

Variable

Primary outcomea

Secondary outcome

All stroke

Ischemic stroke

Hemorrhagic stroke

Myocardial infarction

Statin

0.73 [0.59–0.89], P = 0.002

0.81 [0.63–1.03], P = 0.083

0.76 [0.58–0.99], P = 0.039

1.12 [0.62–2.00], P = 0.710

0.56 [0.38–0.82], P = 0.003

Cumulative statin exposure

  < 1 year

1 (Ref)

1 (Ref)

1 (Ref)

1 (Ref)

1 (Ref)

 1–3 year(s)

0.73 [0.57–0.94], P = 0.015

0.80 [0.60–1.07], P = 0.131

0.82 [0.60–1.12], P = 0.219

0.69 [0.33–1.48], P = 0.345

0.58 [0.35–0.95], P = 0.031

  > 3 years

0.60 [0.47–0.77], P < 0.001

0.66 [0.49–0.88], P = 0.005

0.63 [0.45–0.87], P = 0.005

0.81 [0.41–1.58], P = 0.531

0.46 [0.29–0.74], P < 0.001

  1. Data are expressed as odds ratio [95% confidence interval] obtained from conditional logistic regression analyses using the nested case–control dataset matched for sex, age, insurance type, comorbidities, and treatment with antiplatelets and renin–angiotensin–aldosterone system inhibitors
  2. aComposite of stroke or myocardial infarction