Fig. 7

The expression of glycosyltransferase C1GALT1 is down-regulated by Escherichia coli through the NF-κB pathway. A, B The impact of both enteropathogenic and commensal E. coli on C1GALT1 expression in HT29 cells. C, D The effects of EPEC on the phosphorylation levels of cellular P65 and IκB. E The levels of P65, p-P65, and C1GALT1 after co-treatment of cells with EPEC and/or NF-κB inhibitor BAY 11–7082. EPEC, enteropathogenic Escherichia coli. Statistical comparisons were determined by analysis of variance (ANOVA) among ≥ 3 groups or Student’s t test between two groups. NS, not significant; *P < 0.05; **P < 0.01; ***P < 0.001