Fig. 6

Co-treatment with Escherichia coli and O-glycan inhibitor benzyl-α-GalNAc promotes colitis in mice. A The effects of benzyl-α-GalNAc and/or EPEC E. coli on colonic thickening in mice. B Statistical results. The mice were subjected to intraperitoneal injections of O-glycan inhibitor benzyl-α-GalNAc (1 mg/kg) and/or EPEC E. coli by gavage (1 × 109 cfu/mL in sterile PBS) once daily for 7 consecutive days. IP, intraperitoneal injections; cfu, colony forming units. Differences among the multiple groups were analyzed by one-way ANOVA. *P < 0.05; **P < 0.01; ***P < 0.001