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Table 3 Gene expression of IDO, CIITA and HLA-DR in MSCs of P2

From: Expression of HLA-DR by mesenchymal stromal cells in the platelet lysate era: an obsolete release criterion for MSCs?

MSC donors

2,3-IDO ng/µL

CIITA ng/µL

HLA-DR %

MSCs-310821-P2/PL-240

ND

46.9

6.9

MSCs-310821-P2/PL-240 + TGF-β1

ND

17.1

2.7

MSCs-310821-P2/PL-240 + IFN-γ

50.9

95.6

58.3

MSCs-310821-P2/PL-240 + IFN-γ + TGF-β1

35.1

67.3

40.1

MSCs-181116-P2/PL-269

ND

55.8

a6.3

MSCs-181116-P2/PL-269 + TGF-β1

ND

16.1

4.9

MSCs-181116-P2/PL-269 + IFN-γ

42.6

74.8

95.4

MSCs-181116-P2/PL-269 + IFN-γ + TGF-β1

36.9

64.5

93.4

MSCs-220922-P2/PL-269

1.4

55.2

29.5

MSCs-220922-P2/PL-269 + TGF-β1

ND

36.8

33.6

MSCs-220922-P2/PL-269 + IFN-γ

52.0

76.9

91.2

MSCs-220922-P2/PL-269 + IFN-γ + TGF-β1

42.9

62.5

90.3

  1. aMSCs of donor 181,116 after generation from BM-MNCs at P0 expressed high levels of HLA-DR, P0 = 31%
  2. ND = not detected