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Fig. 5 | Journal of Translational Medicine

Fig. 5

From: Systematic analysis of various RNA transcripts and construction of biological regulatory networks at the post-transcriptional level for chronic obstructive pulmonary disease

Fig. 5

RBP-hub gene interaction network and the ceRNA network. A RBP-hub gene interaction network constructed by hub genes in COPD patients. Red nodes in the network represent the hub genes, while yellow nodes represent the corresponding RBPs. B RBP-hub gene interaction network constructed by the hub genes shared by smokers and COPD patients. Blue nodes in the network represent the hub genes, while red nodes represent the corresponding RBPs. Connections between different colored nodes indicate that RBPs may regulate hub gene expression by binding to specific RNA structural motifs or elements. C Differentially expressed lncRNA-miRNA-mRNA network in COPD patients. D Differentially expressed lncRNA-miRNA-mRNA network shared by smokers and COPD patients

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Journal of Translational Medicine

ISSN: 1479-5876

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