Fig. 1

A–D Representative X-rays of femora of controls (A, B) and PTH-treated mice (C, D) at 2 (A, C) and 10 weeks (B, D) after surgery. Scale bars: 1 mm. Representative µCT-3D reconstructions (E, G, I, K) and transversal µCT images (F, H, J, L) of controls (E–H) and PTH-treated animals (I–L) at 2 (E, F, I, J) and 10 weeks (G, H, K, L) after surgery. Scale bars: 0.5 mm. M, N Poorly (PM) and highly mineralized (HM) bone volume of the callus tissue of controls (white bars, n = 5 at 2 weeks after surgery, n = 9 at 10 weeks after surgery) and PTH-treated mice (black bars, n = 5 at 2 weeks after surgery, n = 9 at 10 weeks after surgery) at 2 (M) and 10 weeks (N) after surgery, as assessed by µCT analyses. Mean ± SEM; *p < 0.05 vs. control