Table 3 Cox proportional hazard ratios (HRs) of the identified cMetS-S trajectory patterns for incidence type 2 diabetes mellitus in normoglycemic and prediabetic individuals
From: Trajectory patterns of metabolic syndrome severity score and risk of type 2 diabetes
Events | IR (95% CI)a | HR (95% CI) | Test PH p-valueb | ||||
|---|---|---|---|---|---|---|---|
Model 1 | Model 2 | Model 3 | Model 4 | ||||
Normoglycemic subjects at baseline (n = 3260) | |||||||
Class 1 (n = 867) | 15 | 2.1 (1.2–3.4) | 1.0 (Reference) | 1.0 (Reference) | 1.0 (Reference) | 1.0 (Reference) | – |
Class 2 (n = 1558) | 83 | 6.1 (4.9–7.6) | 2.67 (1.53–4.68) | 2.64 (1.51–4.62) | 2.39 (1.36–4.21) | 2.20 (1.25–3.88) | 0.41 |
Class 3 (n = 835) | 159 | 20.1 (17.2–23.4) | 9.46 5.44–16.43) | 9.24 (5.31–16.07) | 7.93(4.51–13.94) | 7.12 (6.05–12.52) | 0.78 |
Prediabetic subjects at baseline (n = 671) | |||||||
Class 1 (n = 64) | 16 | 15.6 (9.6–25.5) | 1.0 (Reference) | 1.0 (Reference) | 1.0 (Reference) | 1.0 (Reference) | – |
Class 2 (n = 307) | 94 | 37.8 (30.9–46.3) | 2.54 (1.46–4.41) | 2.51 (1.45–4.37) | 2.60 (1.50–4.52) | 2.53 (1.46–4.66) | 0.09 |
Class 3 (n = 300) | 105 | 60.6 (50.1–73.4) | 4.04 (2.32–7.03) | 3.74 (2.13–6.56) | 3.99 (2.27–7.00) | 3.78 (2.15–6.65) | 0.14 |