Fig. 4

Immune association of ECMGs classifications. A Violin plots comparing the ESTIMATE score, stromal score, immune score, and tumor purity between C1 and C2. B Box plot comparing the activity scores of the steps in the cancer-immunity cycle between C1 and C2. C Box plot comparing scores for 16 immune cell types between C1 and C2. D Box plot comparing scores for 13 immune-related functions between C1 and C2. E Verification of ssGSEA results by seven other algorithms, namely TIMER, CIBERSORT, CIBERSORT-ABS, QUANTISEQ, MCPCOUNTER, XCell, and EPIC. F Heatmap showing the correlation between the two clusters and immune modulators. *P < 0.05, **P < 0.01, ***P < 0.001. ns not significant