Fig. 2

Overview of the most common model types. Both ECLM (established cell line models) and PTM (primary patient-derived tumor models) require immunocompromised hosts. PTM include cell injection models and whole tumor ‘PDX’ models. Syngeneic modelling is achievable in immunocompetent hosts. RCAS/TVA: Replication-competent avian leukosis virus splice-acceptor/tumor virus A. Illustrator: Mikkel Schou Andersen