Fig. 4

Forest plot of Two-Sample Mendelian Randomization study based on the MR method form CRC to LC. A, B, C Mendelian randomization estimates of genetically predicted CRC on overall LC (A), LUSC (B) and LUAD (C) risk. D, E, F Mendelian randomization estimates of genetically predicted CC on overall LC (D), LUSC (E) and LUAD (F) risk. G, H, I Mendelian randomization estimates of genetically predicted RC on overall LC (G), LUSC (H) and LUAD (I) risk. LC lung cancer, CRC colorectal cancer, IVW inverse variance weighted, MR-PRESSO Mendelian Randomization Pleiotropy RESidual Sum and Outlier, MR-RAPS Mendelian Randomization robust adjusted profile score, LUAD adenocarcinoma of lung, LUSC squamous cell lung carcinoma, CC colon cancer, RC rectal cancer