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Table 1 Demographic and clinical characteristics of study cohorts

From: Profiling the metabolic disorder and detection of colorectal cancer based on targeted amino acids metabolomics

Items

Training set

Validation set

CRC

HV

CRC

PC

HV

n

130

216

116

33

195

Gender (n, male/female)

72/58

124/92

83/33

22/11

89/106

Age (mean ± SD)

59.68 ± 11.53

58.07 ± 10.65

61.38 ± 12.51

50.94 ± 12.18

48.02 ± 14.87

Range

28–89

24–83

26–89

24 ~ 72

24 ~ 76

CEA (median, range)

3.22, 0.49 ~ 2056

0.70, 0.08 ~ 8.96

2.28, 0.94–277.5

2.15, 0.23–6.52

0.43, 0.06–7.87

AFP (median, range)

2.54, 1.04 ~ 8.00

2.98, 0.15 ~ 11.75

3.03, 1.06–7.95

3.15, 2.13–6.36

2.53, 0.06–5.82

Presampling chemotherapy(n)

13

 

10

  

CRC stages(n)

 I

26

 

19

  

 II

39

 

43

  

 III

42

 

44

  

 IV

14

 

7

  

 NA

9

 

3

  

Pathological pattern

Adenocarcinoma

112

    

Tubular adenocarcinoma

6

    

Mucinous adenocarcinoma

5

    

Unknown

7

    

PC category(n)

Polyp

   

20

 

Inflammatory colitis

   

7

 

 Intestinal obstruction

   

1

 

Mixed hemorrhoids

   

5

 

Smoker(n)

26

35

   

Alcohol consumption(> 100 g/day)

23

30

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