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Table 1 Clinical characteristics of the study population

From: Myeloid PTP1B deficiency protects against atherosclerosis by improving cholesterol homeostasis through an AMPK-dependent mechanism

Clinical characteristics (whole cohort)

 

Healthy volunteers

Patients affected with atherosclerosis

Male (n = 14)

Female (n = 16)

Overall (n = 30)

Male (n = 17)

Female (n = 13)

Overall (n = 30)

Mean age (years)

30.31 (± 7.21)

33.29 (± 8.46)

31.51 (± 7.90)

62.92 (± 11.08)

69.6 (± 9.41)

65.81 (± 8.01)

Mean height (cm)

183.57 (± 6.44)

167.83 (± 6.29)

175.16 ± (6.37)

174.83 (± 6.71)

163.29 (± 4.99)

169,82 (± 6,62)

Mean weight (kg)

84.78 (± 8.51)

66.14 (± 3.99)

74.84 (± 6.84)

80.71 (± 6.89)

62.19 (± 5.71)

72.68 (± 6.33)

BMI

23.22 (± 4.10)

23.19 (± 3.01)

23.21 (± 3.63)

26.03 (± 2.81)

23.82 (± 2.91)

25.07 (± 2.89)

Hip-to-waist ratio

0.91 (± 0.08)

0.83 (± 0.05)

0.87 (± 0.07)

0.99 (± 0.13)

0.84 (± 0.06)

0.93 (± 0.09)

Number of subjects with a history of smoking (n, %)

2

3

5

12 (71%)

10 (77%)

22 (73%)

Patients affected with atherosclerosis

   

Type of CAD

   

st.p. Major adverse cardiovascular event (n, %)

12 (71%)

6 (46%)

18 (60%)

Chronic coronary syndrome (n, %)

5 (29%)

7 (54%)

13 (43%)

Mean years since first diagnosis

5.71 (± 4.33)

3.47 (± 3.07)

4.73 (± 3.62)

Number of subjects…

Treated with antiplatelet therapy (n, %)

13 (76%)

6 (46%)

19 (63%)

Of which treated with dual antiplatelet therapy (n, %)

4 (24%)

2 (15%)

6 (20%)

With coronary stents (n, %)

15 (88%)

9 (69%)

24 (80%)

After coronary bypass surgery (n, %)

6 (45%)

3 (23%)

9 (30%)

With arterial hypertension (n, %)

15 (88%)

10 (76%)

25 (83%)

With diabetes mellitus (n, %)

8 (47%)

4 (30%)

12 (40%)

With metabolic syndrome (n, %)

8 (47%)

3 (23%)

11 (37%)

  1. Data are represented as mean (± SD) unless otherwise specified