Fig. 1

Myeloid PTP1B deletion results in significantly decreased circulating LDL/VLDL-C levels. Myeloid PTP1B ablation ameliorates high fat diet induced dyslipidaemia Blood was collected at terminal culls and serum was analyzed for circulating total cholesterol (A), LDL/VLDLcholesterol (B), HDL-cholesterol (C) and triglyceride levels (D). Data were normalized to the average of wild types for each respective sex and were then pooled due to the highly comparable relative differences between sexes and genotypes (Additional file 2: Fig. S2, Additional file 3: Fig. S3). Data are represented as mean ± S.E.M. and were analyzed by bootstrapped t-tests