Skip to main content

Table 2 Associations of polymorphisms in the HMGCR and FADS genes with TNF-α and IL10 levels

From: Association between HMGCR, CRP, and CETP gene polymorphisms and metabolic/inflammatory serum profile in healthy adolescents

Gene

SNP ID

Minor Allele

Risk genotype

Serum concentration effect

*Mean increase

(95% CI)

p-value

HMGCR

rs3846663

T

CT

↑TNF-α

 + 0.49

0.05–0.92

0.033

FADS

rs7481842

C

CG

↑IL-10

 + 1.09

0.34–1.85

0.006

  1. SNP, Single Nucleotide polymorphism; CI, confidence interval.
  2. *Derived from the slope of the linear regression analysis