Table 2 Patient characteristics according to CPG or LSD genes carrier status
Variable | CPG carriera | LSD gene carriera | Non-carrier | P-value |
|---|---|---|---|---|
|  | n = 15 | n = 32 | n = 371 |  |
Age, years, mean ± SD | 60.3 ± 7.2 | 61.7 ± 11.5 | 65.3 ± 9.54 | 0.025 |
Sex | Â | |||
 Male | 9 (2.2) | 22 (5.3) | 212 (50.7) | 0.438 |
 Female | 6 (1.4) | 10 (2.4) | 159 (38.0) |  |
 BMI, kg/m2, mean ± SD | 23.0 ± 2.8 | 22.3 ± 2.6 | 22.8 ± 3.0 | 0.628 |
DM, no. (%) | Â | |||
 Yes | 5 (1.2) | 14 (3.3) | 127 (30.4) | 0.551 |
 No | 10 (2.4) | 18 (4.3) | 244 (58.4) |  |
Smoking, no. (%) | 0.597 | |||
 Yes | 3 (0.7) | 11 (2.6) | 108 (25.8) |  |
 No | 12 (2.9) | 21 (5.0) | 263 (62.9) |  |
Alcohol, no. (%) | 0.809 | |||
 Yes | 4 (1.0) | 10 (2.4) | 126 (30.1) |  |
 No | 11 (2.6) | 22 (5.3) | 245 (58.6) |  |
 CEA, ng/mL, mean ± SD | 9.7 ± 25.5 | 4.0 ± 6.5 | 9.9 ± 55.2 | 0.872 |
 CA 19–9, U/mL, mean ± SD | 555.0 ± 1136.3 | 4092.3 ± 8559.6 | 2677.3 ± 11,499.8 | 0.588 |
AJCC 8th stage, no. (%) | 0.840 | |||
 I | 4 (1.0) | 8 (1.9) | 66 (15.8) |  |
 II | 4 (1.0) | 11 (2.6) | 108 (25.8) |  |
 III | 4 (1.0) | 7 (1.7) | 101 (24.2) |  |
 IV | 3 (0.7) | 6 (1.4) | 96 (23.0) |  |